Some of us look on the bright side of things, but all handicappers have to consider their selections' flaws before making their picks. With this in mind, here's our take on how every team could get beat in Week Three: 

N.Y. JETS -2 ½ vs. Tennessee (37)

If the Jets are emotionally wrung out after beating the Pats, the Titans have a great chance at springing the upset. This assumes, of course, that Jets QB Mark Sanchez won't pick apart the struggling Titans' secondary.

HOUSTON -4 vs. Jacksonville (47)

If you like the Jaguars, you are very skeptical of the Texans' defense, not to mention their traditional problems handling success. But if you like the Jaguars, aren't you a little worried about the offense scoring enough, Houston's "D" issues or not?

PHILADELPHIA -8 ½ vs. Kansas City ( 40 ½ )

The Chiefs are catching the Eagles at a good time. Philly has multiple injuries on offense, with QB Donovan McNabb likely out a second straight game and RB Brian Westbrook's status up in the air. However, reserve QB Kevin Kolb played well last week, and rookie back LeSean McCoy is highly regarded. And the Eagles will also have Michael Vick in reserve should Kolb struggle, too. This game comes down to whether the Chiefs' defense can get enough stops.

BALTIMORE -13 ½ vs. Cleveland (38 ½ )

The case for the favorite is simple: The Ravens are rolling right now and have significant edges on both sides of the ball. The Browns have to play like they did in the first half vs. Minnesota in Week One and force some turnovers.

N.Y. Giants -6 ½ vs. TAMPA BAY (44 ½ )

Both teams have a host of injury concerns. The Bucs' weakness on defense, though, is more glaring than any of the Giants' problems. The biggest worry with the Giants could be a letdown in a second of back-to-back road games.

Washington -6 ½ vs. DETROIT (38 ½ )

Could this be the week the Lions finally get a win? Only if QB Matt Stafford makes some big-time strides against a sound, veteran Washington defense. But here's the thing: even if you love the Redskins' defense, aren't you a little worried about the Washington offense?

Green Bay -6 ½ vs. ST. LOUIS (41)

It's tough enough to lay almost a TD on the road without having to worry about whether the quarterback is going to be blindsided a couple times a game. But that's where we are with the Packers. The question is, can the Rams pressure QB Aaron Rodgers — and can they score some more points? One TD over two games ... ugh.

MINNESOTA -7 vs. San Francisco (39)

The Vikings haven't faced a defense like San Francisco's, and the news that WR Percy Harvin missed practice Thursday and Friday is not good news for Minnesota backers. Harvin is exceptionally talented. But Harvin or nor Harvin, if the Vikings put two halves of good football together, the Niners might not be able to keep up.

NEW ENGLAND -4 ½ vs. Atlanta (46)

I was strident about my Patriots over the Jets pick last week, and I got beat. Wasn't the first time, and won't be the last. If I were in Vegas this weekend, would I play the Patriots back off that tough loss? Well, it depends if I thought the Falcons could generate a consistent pass rush — and whether Tom Brady could make strong throws in the face of that rush.

Chicago -2 vs. SEATTLE (37)

How sharp will the Bears traveling cross-country after tough games vs. Green Bay and Pittsburgh? The concern with the Seahawks, like it was last season, is injuries, particularly the rib injury to QB Matt Hasselbeck.

New Orleans -6 vs. BUFFALO (52)

The Saints have been ultraimpressive to start this season, but this is a lot of points to lay against a respectable opponent in what has been a tough place to play for many, many years. The Bills' offense will need to step it up to keep it close, though — and yes, I'm aware it has done its part in the first two games of the '09 campaign.

SAN DIEGO -6 vs. Miami (44)

The Chargers will again be without RB LaDainian Tomlinson and have serious O-line issues. But it would be easier to like Miami if it wasn't coming off a tough loss and having to travel cross country after a Monday-night game. The Dolphins cannot start slowly if they want to win this game.

Pittsburgh -4 vs. CINCINNATI (37)

Interesting, interesting game. The Bengals' hopes rest on their improved defense and the strides the offense made in Week Two. If either unit regresses, it will be tough to spring the upset. But Pittsburgh better get more out of its running game and tighten up in pass coverage.

Denver -1 ½ vs. OAKLAND (36)

The over-under in this game tells you all you need to know about both offenses. The Broncos may be 2-0, but they are feeling their way, and if they play like they did at Cincinnati, the Raiders might pull off the upset. That said, Oakland's inconsistency is one of its trademarks.

ARIZONA -2 ½ vs. Indianapolis (48)

Is the Colts' run defense again a big problem? It sure looked that way Monday night. More struggles in the trenches will probably be too much to overcome at Arizona. However, the Cards' defense, solid to begin this season, gets a major test from Peyton Manning and Co. Is it up to the task?

DALLAS -9 vs. Carolina (47½)

The Cowboys' defense has really struggled, which gives the Panthers a chance to hang around in this one — assuming QB Jake Delhomme doesn't pass them out of contention.