The Colts signed RBs Deji Karim and Mewelde Moore and placed RB Donald Brown and FB Robert Hughes on injured reserve.
Brown played in 10 games with four starts this season and had 417 yards rushing, 93 yards receiving and one rushing touchdown. He suffered an ankle injury this season.
Hughes played in five games with one start this season and had one carry and one reception.
Karim appeared in 12 games for the Jaguars last season and had 130 yards rushing and 120 yards receiving. Moore played in six games earlier this season for the Colts and had nine carries for 14 yards and four catches for 36 yards and one touchdown.