Steelers head coach Mike Tomlin confirmed that CB Ike Taylor has a right ankle fracture and will be out at least two weeks.
Taylor, who has not missed a game since 2004, has 32 tackles, 13 passes defensed and one interception this season.
Tomlin said that Cortez Allen will start and Curtis Brown will play the nickel. The Steelers will reportedly work out veteran CB Stanford Routt, who began the year with the Chiefs.
Pittsburgh is tied with the Bengals for the second AFC wild-card spot and hosts the Chargers in Week 14.