Updated Saturday, Nov. 10 at 12:23 p.m. ET

Byes: Arizona, Cleveland, Green Bay, Washington

Here are PFW's Week 10 QB rankings:

1. Tom Brady, Patriots vs. Bills
2. Matt Ryan, Falcons at Saints
3. Drew Brees, Saints vs. Falcons
4. Peyton Manning, Broncos at Panthers
5. Ben Roethlisberger, Steelers vs. Chiefs
6. Philip Rivers, Chargers at Buccaneers
7. Andrew Luck, Colts at Jaguars
8. Matthew Stafford, Lions at Vikings
9. Eli Manning, Giants at Bengals
10. Tony Romo, Cowboys at Eagles
11. Josh Freeman, Buccaneers vs. Chargers
12. Cam Newton, Panthers vs. Broncos
13. Andy Dalton, Bengals vs. Giants
14. Ryan Fitzpatrick, Bills at Patriots
15. Michael Vick, Eagles vs. Cowboys
16. Joe Flacco, Ravens vs. Raiders
17. Ryan Tannehill, Dolphins vs. Titans
18. Alex Smith, 49ers vs. Rams
19. Carson Palmer, Raiders at Ravens
20. Matt Schaub, Texans at Bears
21. Jay Cutler, Bears vs. Texans
22. Jake Locker, Titans at Dolphins
23. Russell Wilson, Seahawks vs. Jets
24. Blaine Gabbert, Jaguars vs. Colts
25. Christian Ponder, Vikings vs. Lions
26. Mark Sanchez, Jets at Seahawks
27. Sam Bradford, Rams at 49ers
28. Matt Cassel, Chiefs at Steelers

Not listed: Brady Quinn, Chiefs.

We base our rankings on the following scoring system: For skill-position players, one point for every 10 rushing/receiving yards, one point for every 30 passing yards, six points for a TD run or catch, four points for a TD pass, two points for a two-point conversion run or catch, two points for a two-point conversion pass. For kickers, three points for FGs of 18-39 yards, four points for FGs of 40-49 yards, and five points for FGs of 50-plus yards. Defensive rankings are based primarily on points allowed, yardage allowed and sack potential.

Glossary of notations

INJ — player has an injury that may affect productivity or availability.
ILL — player has an illness that may affect productivity or availability.
UP — player was moved up on draft board after original posting.
DOWN — player was moved down on draft board after original posting.
Not listed — player is temporarily sidelined due to injury or suspension but otherwise would be ranked.
ACTIVE — on game day, player has been designated active (posted shortly before kickoff, when available).
INACTIVE — on game day, player has been designated inactive (posted shortly before kickoff, when available).

Players and/or notations added after the original posting are shown in boldface.

Note: Remember to check back for late-week and weekend updates, as well as game inactives (when available) in the 90 minutes preceding the 1 p.m. Sunday kickoffs.