Updated at 11:44 a.m. EST on Saturday, Oct. 13 

Byes: Carolina, Chicago, Jacksonville, New Orleans.

Here are PFW's Week Six RB rankings:

1. Arian Foster, Texans vs. Packers
2. Jamaal Charles, Chiefs at Buccaneers
3. LeSean McCoy, Eagles vs. Lions
4. Marshawn Lynch, Seahawks vs. Patriots
5. Trent Richardson, Browns vs. Bengals
6. Adrian Peterson, Vikings at Redskins (UP)          
7. Ray Rice, Ravens vs. Cowboys
8. Darren McFadden, Raiders at Falcons
9. Reggie Bush, Dolphins vs. Rams
10. Frank Gore, 49ers vs. Giants
11. Ryan Mathews, Chargers vs. Broncos
12. Alfred Morris, Redskins vs. Vikings
13. BenJarvus Green-Ellis, Bengals at Browns
14. Stevan Ridley, Patriots at Seahawks
15. DeMarco Murray, Cowboys at Ravens
16. Willis McGahee, Broncos at Chargers
17. Michael Turner, Falcons vs. Raiders
18. C.J. Spiller, Bills at Cardinals
19. Rashard Mendenhall, Steelers at Titans
20. Doug Martin, Buccaneers vs. Chiefs
21. Mikel Leshoure, Lions at Eagles
22. Ahmad Bradshaw, Giants at 49ers
23. Fred Jackson, Bills at Cardinals
24. Steven Jackson, Rams at Dolphins
25. Vick Ballard, Colts at Jets
26. Alex Green, Packers at Texans
27. Shonn Greene, Jets vs. Colts
28. Isaac Redman, Steelers at Titans
29. Chris Johnson, Titans vs. Steelers
30. Kendall Hunter, 49ers vs. Giants
31. William Powell, Cardinals vs. Bills
32. Ben Tate, Texans vs. Packers  (UP)
33. Jackie Battle, Chargers vs. Broncos
34. LeGarrette Blount, Buccaneers vs. Chiefs
35. LaRod Stephens-Howling, Cardinals vs. Bills (UP)
36. Danny Woodhead, Patriots at Seahawks
37. Ronnie Hillman, Broncos at Chargers
38. Daryl Richardson, Rams at Dolphins
39. Lamar Miller, Dolphins vs. Rams
40. Jacquizz Rodgers, Falcons vs. Raiders
41. Marcel Reece, Raiders at Falcons
42. Brandon Bolden, Patriots at Seahawks (DOWN) — INJ
43. Bilal Powell, Jets vs. Colts
44. Joique Bell, Lions at Eagles
45. Robert Turbin, Seahawks vs. Patriots
46. Toby Gerhart, Vikings at Redskins
47. Bernard Pierce, Ravens vs. Cowboys
48. Shaun Draughn, Chiefs at Buccaneers
49. Alfonso Smith, Cardinals vs. Bills
50. David Wilson, Giants at 49ers
51. James Starks, Packers at Texans
52. Delone Carter, Colts at Jets
53. Ronnie Brown, Chargers vs. Broncos
54. Mike Goodson, Raiders at Falcons
55. Brian Leonard, Bengals at Browns
56. Justin Forsett, Texans vs. Packers
57. Ryan Grant, Redskins vs. Vikings
58. Lance Ball, Broncos at Chargers
59. Mewelde Moore, Colts at Jets
60. Chris Ogbonnaya, Browns vs. Bengals        

Not listed: Cedric Benson, Packers; Jahvid Best, Lions; Donald Brown, Colts; Peyton Hillis, Chiefs; Bernard Scott, Bengals; Daniel Thomas, Dolphins; Beanie Wells, Cardinals; Ryan Williams, Cardinals

The above player rankings are based on expectations for this week only, not for the entire season, taking into account this week's specific matchups and injuries. The initial rankings are compiled before the release of the NFL's early injury report and are updated Thursday to reflect the status of each player.

We base our rankings on the following scoring system: For skill-position players, one point for every 10 rushing/receiving yards, one point for every 30 passing yards, six points for a TD run or catch, four points for a TD pass, two points for a two-point conversion run or catch, two points for a two-point conversion pass. For kickers, three points for FGs of 18-39 yards, four points for FGs of 40-49 yards, and five points for FGs of 50-plus yards. Defensive rankings are based primarily on points allowed, yardage allowed and sack potential.

Glossary of notations

INJ — player has an injury that may affect productivity or availability.
ILL — player has an illness that may affect productivity or availability.
UP — player was moved up on draft board after original posting.
DOWN — player was moved down on draft board after original posting.
Not listed — player is temporarily sidelined due to injury or suspension but otherwise would be ranked.
ACTIVE — on game day, player has been designated active (posted shortly before kickoff, when available).
INACTIVE — on game day, player has been designated inactive (posted shortly before kickoff, when available).

Players and/or notations added after the original posting are shown in boldface.

Note: Remember to check back for late-week and weekend updates, as well as game inactives (when available) in the 90 minutes preceding the 1 p.m. Sunday kickoffs.