Updated Sunday, Sept. 30 at 12:14 p.m. ET

Byes: Indianapolis, Pittsburgh

Here are PFW's Week Four RB rankings:

1. Arian Foster, Texans vs. Titans
2. Ray Rice, Ravens vs. Browns
3. Darren McFadden, Raiders at Broncos
4. Maurice Jones-Drew, Jaguars vs. Bengals
5. LeSean McCoy, Eagles vs. Giants
6. Adrian Peterson, Vikings at Lions
7. DeMarco Murray, Cowboys vs. Bears
8. Jamaal Charles, Chiefs vs. Chargers
9. Marshawn Lynch, Seahawks at Rams
10. Doug Martin, Buccaneers vs. Redskins
11. Ryan Mathews, Chargers at Chiefs
12. BenJarvus Green-Ellis, Bengals at Jaguars
13. Darren Sproles, Saints at Packers
14. Trent Richardson, Browns at Ravens
15. Frank Gore, 49ers at Jets
16. Ryan Williams, Cardinals vs. Dolphins
17. Stevan Ridley, Patriots vs. Bills
18. Andre Brown, Giants at Eagles
19. Mikel Leshoure, Lions vs. Vikings — (ACTIVE)
20. Michael Turner, Falcons vs. Panthers
21. Jonathan Stewart, Panthers at Falcons
22. Cedric Benson, Packers vs. Saints
23. Willis McGahee, Broncos vs. Raiders
24. Alfred Morris, Redskins at Buccaneers
25. Ben Tate, Texans vs. Titans
26. DeAngelo Williams, Panthers at Falcons
27. Pierre Thomas, Saints at Packers
28. Michael Bush, Bears at Cowboys       
29. Ahmad Bradshaw, Giants at Eagles
30. Jacquizz Rodgers, Falcons vs. Panthers
31. Chris Johnson Titans at Texans
32. Daniel Thomas, Dolphins at Cardinals
33. C.J. Spiller, Bills vs. Patriots — (ACTIVE)
34. Steven Jackson, Rams vs. Seahawks — (ACTIVE)
35. Fred Jackson, Bills vs. Patriots — (ACTIVE)
36. Mark Ingram, Saints at Packers
37. Matt Forte, Bears at Cowboys — INJ
38. Lamar Miller, Dolphins at Cardinals
39. Shonn Greene, Jets vs. 49ers 
40. Toby Gerhart, Vikings at Lions
41. Reggie Bush, Dolphins at Cardinals — INJ
42. Danny Woodhead, Patriots vs. Bills
43. Kendall Hunter, 49ers at Jets
44. Marcel Reece, Raiders at Broncos
45. Evan Royster, Redskins at Buccaneers — (UP)
46. Daryl Richardson, Rams vs. Seahawks
47. Mike Tolbert, Panthers at Falcons
48. Jackie Battle, Chargers at Chiefs
49. Bernard Pierce, Ravens vs. Browns
50. Shaun Draughn, Chiefs vs. Chargers
51. Kevin Smith, Lions vs. Vikings
52. Tashard Choice, Bills vs. Patriots — (DOWN)
53. LeGarrette Blount, Buccaneers vs. Redskins
54. Bilal Powell, Jets vs. 49ers
55. David Wilson, Giants at Eagles
56. Joique Bell, Lions vs. Vikings
57. Curtis Brinkley, Chargers at Chiefs
58. Kahlil Bell, Bears at Cowboys
59. Ronnie Hillman, Broncos vs. Raiders
60. Lance Ball, Broncos vs. Raiders
61. Ryan Grant, Redskins at Buccaneers
62. Javon Ringer, Titans at Texans                           
63. Knowshon Moreno, Broncos vs. Raiders
64. Robert Turbin, Seahawks at Rams
65. Jason Snelling, Falcons vs. Panthers
66. Rashad Jennings, Jaguars vs. Bengals             
67. Chris Ogbonnaya, Browns at Ravens
68. Felix Jones, Cowboys vs. Bears
69. Mike Goodson, Raiders at Broncos — INJ
70. Peyton Hillis, Chiefs vs. Chargers — INJ
71. Brandon Jacobs, 49ers vs. Jets — INJ
72. Shane Vereen, Patriots at Bills — INJ
73. LaRod Stephens-Howling, Cardinals vs. Dolphins — INJ
74. Bernard Scott, Bengals at Jaguars — INJ

Not listed: Roy Helu, Redskins; Beanie Wells, Cardinals

The above player rankings are based on expectations for this week only, not for the entire season, taking into account this week's specific matchups and injuries. The initial rankings are compiled before the release of the NFL's early injury report and are updated Thursday to reflect the status of each player.

We base our rankings on the following scoring system: For skill-position players, one point for every 10 rushing/receiving yards, one point for every 30 passing yards, six points for a TD run or catch, four points for a TD pass, two points for a two-point conversion run or catch, two points for a two-point conversion pass. For kickers, three points for FGs of 18-39 yards, four points for FGs of 40-49 yards, and five points for FGs of 50-plus yards. Defensive rankings are based primarily on points allowed, yardage allowed and sack potential.

Glossary of notations

INJ — player has an injury that may affect productivity or availability.
ILL — player has an illness that may affect productivity or availability.
UP — player was moved up on draft board after original posting.
DOWN — player was moved down on draft board after original posting.
Not listed — player is temporarily sidelined due to injury or suspension but otherwise would be ranked.
ACTIVE — on game day, player has been designated active (posted shortly before kickoff, when available).
INACTIVE — on game day, player has been designated inactive (posted shortly before kickoff, when available).

Players and/or notations added after the original posting are shown in boldface.

Note: Remember to check back for late-week and weekend updates, as well as game inactives (when available) in the 90 minutes preceding the 1 p.m. Sunday kickoffs.