The Colts signed RB Darren Evans from their practice squad on Tuesday and waived OT Michael Toudouze.
Evans joined the team as an undrafted free agent on July 29. He was inactive for the first two weeks of the season and then was signed to the practice squad.
The Colts also waived Kade Weston from the practice squad and Corelius Brown from the team's injured-reserve list.
Evans will provide depth at running back after Joseph Addai got hurt in the Colts' loss to the Chiefs.