The 49ers placed DL Will Tukuafu on injured reserve and promoted rookie S Colin Jones from the practice squad, the team announced Tuesday.
Tukuafu spent most of 2010, his rookie season, on the Niners' practice squad. He had two tackles and a fumble recovery in four games this season. He injured his wrist in Sunday's win over the Eagles.
Jones was the team's sixth-round pick in April.