The Titans placed starting C Eugene Amano on injured reserve Tuesday with a back injury. Amano had started all 13 games this season after moving over from left guard.
Fernando Velasco will likely replace Amano. Velasco has played in all 13 games and started in Week Five against the Cowboys.
The Titans signed DT Malcolm Sheppard from the Texans' practice squad. He played in one game for Houston this season.