RB Peyton Hillis is the only Browns player who merits starting consideration in most fantasy leagues in Week Six. Hillis, who's expected to play despite a thigh injury that caused him to miss practice Wednesday and Thursday, could carry a heavy workload with rookie QB Colt McCoy expected to start. The Steelers are strong vs. the run (allowing just 2.6 yards per carry), and if you have solid RB depth, Hillis might not be a slam-dunk start, but he figures to get quite a few touches, mostly as a runner but perhaps also as a receiver, a role that he has played effectively this season, too.
Keep an eye on how McCoy fares and file it away, but he's not a viable fantasy starter this week.
With McCoy making his first start, the Browns' offense, which is already on the conservative side, probably won't take many downfield shots, so it's best to sit WR Mohamed Massaquoi in Week Six.
WR Joshua Cribbs (8-87-0 rushing in the last meeting with Pittsburgh on Dec. 10, 2009) could get some rushing opportunities out of the Browns' "Flash" set, but the Steelers have had more than 10 months to think about how Cribbs shredded their defense last season, and they also have had an extra week to prepare. In other words, he's not an ideal starting option, either.
TE Benjamin Watson (team-high 23 catches) could have some value in bigger PPR leagues, but again, it's hard to bank on the Browns' offense this week.