While the Bills are making a change under center in an attempt to spark their offense, fantasy owners shouldn't expect any dramatic improvements from Buffalo's skill players.
Just as he was in 2009, QB Trent Edwards was largely ineffective through the first two contests, throwing for just 241 yards, one TD and two INTs in total. He'll go to the bench in favor of Ryan Fitzpatrick, who started eight games a year ago but had multiple TD passes on just one occasion.
Not known to do anything particularly well, Fitzpatrick doesn't improve the fantasy prospects of anyone all that much, not that there are that many Bills worth owning in the first place. Only because Fitz is more willing to throw deep than Edwards was, speedy WR Lee Evans might get a slight upgrade.
The bigger concern in Buffalo is what's going on in the backfield. We all knew their three-headed monster would make for a complicated fantasy scenario, but no one could have expected C.J. Spiller to get just one carry in Week Two while Marshawn Lynch got 17. Although speculation is that the Bills were showcasing Lynch for a trade, Spiller owners should be concerned that their guy saw such little action. Right now, the rookie appears to have fallen to No. 3 on the pecking order for carries and can't be trusted in fantasy lineups.